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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da77d9dd667b8b75358f2d2c7912e0db6e60ab7e1921219b0e16a2fa78d4bee' 
  AND token = 'APTz1uO5s0xHRDi7WXb8uWpbpbz+1MgojPN6DQxUQUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}