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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165842371f5fa33f29889e0439c4dea3f394eb68877fb5bf9873731e1f5d4f6d' 
  AND token = 'XPctgAexx8ZZ6SPs2OaeDWwt0q0FW2HZr4qfN7Fz0es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}