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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e212897d114074426db1f29994c62622350675d9281ee42eddaaa892ca523f' 
  AND token = 'HcsQicTiU+k1njxZgWS8RFM8+Kj7YnKJfly4EkQoPwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}