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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1650ab39c759016699a9241f298814621201409a079029c4e6c9426c3cfc1896' 
  AND token = '7tb9xJfU3Cm4phZHO3THl/iN9f6xUUhacz8nGb1lc4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}