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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87242fcba664cb8ba9bac61f2a4f8f528c2f8b7450c360da989b68abba5a37b4' 
  AND token = 'ckup3L2fGucTVcBBOXtvhGjZk6+uvkvWMIYwvUzTz48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}