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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d8dcb230504bd975a49765752fd1f5b07b8c1e0e979050bd94e261ec03b46f' 
  AND token = 'R7Ntr72ss6J6iUGW5s9KWs/m28207Hp233dmt3KZB5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}