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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149556e64998206d2635c9097b48474a87110e1bcae98bd9110f74c0ff0f8d65' 
  AND token = 'mxQC06xmdMIa+FpiEkrw83iO6U4NlCgXRa76oxo7zTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}