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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e59928f8daf87c362aa3a1e07c37beab13a9619c580b5d4276bdf3973cff2d0' 
  AND token = 'YxrODwrd1S5Y2qxJT0i2eNGgDisgb3DnS+Qis+9fc9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}