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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79837922e450d62f957406f79c7d9e9c5b7b365c7fb65e7982c5f5c4c75af3e0' 
  AND token = 'JOaMQR4XZhCLxA2gj8rlPaalxc8mAEpEwZQlw66STT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}