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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ab834d81342ab5d2b3435cdf93eb93a27296d43de6304a18c807881efa52ca' 
  AND token = '+aaI3AHgK+eAbA2XbwxWFouRQKImU7D6rG0e9yUzUak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}