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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5a839ea23fd402df73a3534326d658fcfa3f5e24e21e1d73c9a4c948416c4f' 
  AND token = 'QJ+CTpYU+QOu2l9z3TLX8HUTGeSNhjM42+FG7xe8nMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}