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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25000e5a5dd3f9059ab8f4867f7ed43339f91afdaa42849ab54fc076206e9c8' 
  AND token = 'm2dymUM56ojNi5vWz+7shuMj/GxeozCXuBVywDN53rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}