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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770f6f2858ad45116aa47eacd5f7d582a8f6c5e7ecd512f777920b19117cb592' 
  AND token = 'MKx0bzBXCnVE0YPY1Hrm20xUw22BadBTH3tPxwgSyEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}