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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121ad9eb284ab238a634b26e5125c9bcd14d4aafd0c8913e69623b4e85b431dd' 
  AND token = 'r1dI8JXjwwAYrfbGnO+q9uiudwWuN7gCsTX4BvcS9hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}