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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000cee2ba1e0159722d224076e102dc8f84f05f962f882379ca781b8fb4b4eb1' 
  AND token = 'GSEr6YzvrWlVx1mC3iisKvW/knLWPxSr8pH8FhY7B4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}