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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3ec671ff287944ed33df9d76d9207330a3f1f873ffc1d8f551cc84b3b43387' 
  AND token = '72pJ7efJJROCdgg31nfF0N3czDg46UZLaX59xw/gDcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}