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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328546bf2ffdc96671785625941d1557394cb75fca728fdf7e9e8956b96fe6db' 
  AND token = 'cA7z7e+EqkZ5uO7cPtD5Swyd7YMstiRnUO15veEPO2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}