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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c95a3e500b93790221fc6ee27fcd9b61c416d3421422a49ff27fec77a9aca57' 
  AND token = 'equa6FN1sK+H4GWphDu3npOo+YQhtQEkqxiRHRhyB1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}