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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10dad5a37b2a41f1e9103c0f011593afe4b2d1d39a89a7bae05f5edb6aaeca5b' 
  AND token = '2e3/PMWAeu4eSvw6ntE/7FSYCWTbmAgyZRR/IWGlgYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}