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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6bc6eb9901b68c2a12126427ea3409b7a057e37b9056afd9a39da622cd6493' 
  AND token = 'E5X1ouPVUkQsWjVLCxkcRhBDQDNlPvf1TsEbdG7lNCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}