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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6510808624c6d2d334eaf870f6868e2dfadaa9380a7eca8c2df50cf8ca6a77f3' 
  AND token = 'ivX0CqIARoAGtCGm+QlX17f+CzNeVfvZgKDYZDVr348=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}