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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73abde4577ebb66aa31778f78a7ba2372cd9ce903137e5ef461a0d51edf6564f' 
  AND token = 'OnGy6xCJAumz9d0YjkYW9TcocMXcm2aE8xS2+GVMurY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}