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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08eca4f5b80e897e81458a1ea652895b010aa95e3c66c34558d7ea1eda7c042a' 
  AND token = 'dakD43PXe/icc0mkuuf0a89p+2WmrzMNnT8Bq9b/vT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}