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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3644d0deb709a9813d32de7c0d11b6a270de5f54978d174c856494f506c4a4' 
  AND token = 'qx2G4ikjYbdQCdLepQuwtA0F0T8iSjS3aZ+rozntrFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}