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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e293e0d9f463014bf88a8e3228648fcab40d7d592ea433e496f833295ff07b71' 
  AND token = 'O/CTeoRg3DPskbC4iLkJ9opYY24d9I2GwHVJ/XRS5eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}