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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4384ffa5c10683250b9aacd69efa6b88020db6ff332f31498f35d3fb84533c00' 
  AND token = 'fKHOBxNLKCGiXePsHjSWtsL7aL0m6HGk1Oi77xKHn3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}