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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd33b89ab640a3e192f19deae4882b49b81c005cbedfc920c8325c353c889e362' 
  AND token = 'jFs1ruammm6sW497w/BhWars59h2o9nuqCDMsNEjaZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}