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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b92f340e10e5bd505f98f27591658fba95c241f6f45788393da897a95fbd0d3' 
  AND token = '00y6IfvGsfFgDBdWokh8PwFMn9/hINS4atLUhmaK9DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}