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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ace7987ca69b72e01b450904ffe1993c101846c4f7d36622750b2c166d54010' 
  AND token = 'Bsu6D2UXxOM4w55MDfi4yYcJjxHYoX18r9ex5Xd4q2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}