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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ae732a5aea1788c4bc15401ec2dfb57f709f7f9932c404a9d2224b102e7384' 
  AND token = '/Ejn77sRVsicLPIxQsZeFCkoBi6LlzJnSL+wbi3TVQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}