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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b149cf17730601ff0aa73138d9a11dd5db8c938f8bc488f323f8100f0d89bb' 
  AND token = 'fyI0d0aVUXl6iB8wwJdFTpcvbbCqjJcmTzVPYvqOHVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}