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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c826c13bbdddeee9fca7116a04cfa9c6935a2ba8fdeafc5e5d3b9f593aaa5f' 
  AND token = 'Ul+D220i2cs/xKKhEvyI81hnIFkc0cJi2IMOPXBkqNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}