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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef48b1c919193d0c72832b354217b037565be89d95b4218300668afdcd4079c' 
  AND token = 'CNjLeUMrrERgX8/X+4nQvgL32A+7mxtgJekAKBGrDd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}