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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8ab268c7c0d806cc7ecdbeb0849b2c0026bec0de6b27af70641787b35b20a2' 
  AND token = 'SJ/oTH66U2IyTlmmkGVUmZ5A1JY+14L9s/L17ltRPhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}