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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12233f8de27c8db2b32deb136ff79f119ee5b63ba108da2ad9339e9cc7428022' 
  AND token = '5KJg1kmf+oM192Eail1fo0p+QVfEHwWxk7VUughTuxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}