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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e720286ba1e3c87f5a8ed6525cb798d516053ea109d4214999395b152d23b8ee' 
  AND token = 'MBRxQHy1o5XVNCRlek38roBst3agT1aupVROY5sG2Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}