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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49e1738574c8aaa48dc41b0f0f6a96265c7e7cc9e8ef2485c681e6e8aa9308e' 
  AND token = 'DnCyBX8FB4r0sUDWPoSuxY567GaeAVLUaUohjUc4fOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}