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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e82906fba8280acaa3454af79697213e1f4d85d18669dd6726105fd6e703d72' 
  AND token = 'YD+v5U6WdOP5S5rrvaaPZvlJMYmmdToxkJ1PpVY55LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}