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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339f299117f895221024f115d493fc1431c64e11b3fbeac6fbf9f587831ebe72' 
  AND token = 'nl94MYQX+zR8zyXIisyxF0JN5UweaSh/Z1TSQF5pFqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}