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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72993b53a2d86d4d29af592c3a5e7bbdc87072cc066799221a493c55145be3c3' 
  AND token = 'XtBa2bkuor2DOuQ7H0/F7alRLK0yx5G+2jCIMVIrut8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}