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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb57ecaadac773ec0935c11e1d41476af32495f486f761d85cd9f5ccff46d69' 
  AND token = 'HUHTsQ5+eFHLLqQcLnbBbUaAS1TcXRaugsid4GC1ivs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}