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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b173a5f53fcef116510dde539ccfd5a4fce3ed4542bd3c1bf8a6f521f38c0559' 
  AND token = 'o3TuD/EN7MF8VAHfGT6QJa5kEkTggLfzsAKSShSvTcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}