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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a355667f9f71ac772b9080206b8c325c20d6834d4777b339d7c6c2a28dd4d13' 
  AND token = 'SE9zqw1mu/6x/Exbmxp1Gi36bZuml7oBWrkUCOX4w5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}