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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f808f818184206770aa6312480e0271d1a34c8960f93cd87c992c17df89aee4a' 
  AND token = 'VA6GWIvpgT27br8ee/Hgi8uQNQMz5yBl1pvLlPlyOZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}