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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621ea372c8f4c77310a6d7e8e9e7d089f8d4bc1750754ad1765dc4c93556c663' 
  AND token = 'AKY4LjLYhjH9CovxBr58UZkD8lCnfhR20jbIR4mi4KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}