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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df05831afdf3cd1bbb87767fa183dde91f4ecb4396a5ad202edaf9604fe259c4' 
  AND token = 'FImdx1I1qO742XSqHv0MSFfi6eYokDrTV+vTgrPzNvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}