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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '070ea0bc5751b5a3fc8641868c53b03a9136d881c6ff6a095e6c9d91d376bf4d' 
  AND token = 'XLUlwE/kkwZYB0vwkl0aS3FMd/YO6ZDZCdfZ5cOYfqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}