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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27ebb3bc2dea7f35b33c0fbab9ca32c2b65411c3d73845b9dfb84c123056397' 
  AND token = '7BVLundKUG1oobCr7iE/fTDBxDb1tVdM8OrG1RidWrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}