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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a6280d9f049457aff76d33d95774f7bbf94584cc60013e99b784e6e2103cf10' 
  AND token = 'Oua3D8TuMWxW2Nta0/uy531iMPDwhsUGt5cNs78X6zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}