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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc5474c339886d8b418bde782de5622b21fa5e8ab98770f957440c1655dcd64' 
  AND token = 'Dkbl9T+d8Y3MCtAK2O+pr7NWs3SOYXJYEAB0RaN19KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}